Noncommutative geometry and motives: the thermodynamics of endomotives

We combine aspects of the theory of motives in algebraic geometry with noncommutative geometry and the classification of factors to obtain a cohomological interpretation of the spectral realization of zeros of $L$-functions. The analogue in characteristic zero of the action of the Frobenius on l-adic cohomology is the action of the scaling group on the cyclic homology of the cokernel (in a suitable category of motives) of a restriction map of noncommutative spaces. The latter is obtained through the thermodynamics of the quantum statistical system associated to an endomotive (a noncommutative generalization of Artin motives). Semigroups of endomorphisms of algebraic varieties give rise canonically to such endomotives, with an action of the absolute Galois group. The semigroup of endomorphisms of the multiplicative group yields the Bost-Connes system, from which one obtains, through the above procedure, the desired cohomological interpretation of the zeros of the Riemann zeta function. In the last section we also give a Lefschetz formula for the archimedean local L-factors of arithmetic varieties.Comment: 52 pages, amslatex, 1 eps figure, v2: final version to appea

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries